Article: Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Gant JC; Chen KC; Norris CM; Kadish I; Thibault O; Blalock EM; Porter NM; Landfield PW J. Neurosci., 2011
Control (n = 16) | Rapamycin (n = 21) | |
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Input resistance (MΩ) | 53.85 ± 6.53 | 50.31 ± 3.14 |
Resting membrane potential (mV) | −61.67 ± 0.71 | −62.83 ± 0.70 |
Action potential amplitude (mV) | 81.43 ± 1.79 | 82.03 ± 1.53 |
Electrode resistance (MΩ) | 116.11 ± 6.38 | 112.50 ± 5.45 |
RSS hyperpolarization (mV) | −5.4 ± 0.77 | −4.89 ± 0.42 |
RSS first EPSP (mV) | 5.95 ± 1.10 | 4.55 ± 0.46* |
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No differences were found except in baseline EPSP amplitude.
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↵*p < 0.05; means ± SEM.
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
---|---|---|---|---|---|
Hippocampus CA1 pyramidal cell | input resistance (MΩ) | 53.85 ± 6.53 (16) | 53.85 (MΩ) | Data Table | |
Hippocampus CA1 pyramidal cell | resting membrane potential (mV) | -61.67 ± 0.71 (16) | -61.67 (mV) | Data Table | |
Hippocampus CA1 pyramidal cell | spike amplitude (mV) | 81.43 ± 1.79 (16) | 81.43 (mV) | Data Table | |
Hippocampus CA1 pyramidal cell | access resistance (MΩ) | 116.11 ± 6.38 (16) | -- | Data Table |